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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a9e6f27e6a901c118bf5d318620dfa4e680123500b76528d8e7c93e20b63b91' 
  AND token = 'Afmeg/+OtC5m+trNFB19o/Wa1hiNZQ9RPjYevLJ+Zs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}