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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59150e90f595fda1a1f6281074b201af600f524a50ec59135cceb9be0c18f5ab' 
  AND token = 'odbyd1JxQpClkGP7VtOBk4gUxPnc5vgxLZDFP7LcWeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}