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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df54b95aff64620a2513ea396dc15fce91da0763f99e73fcd17385fd9b987f1b' 
  AND token = 'msv+soDupSDYtg+S4+pKPZ1xoGSuaIDZnI7LeLSVa0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}