SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6494770668b11b4329cf9ce21630827bd94edb108d156e661ebcfb2ffb2513cc' 
  AND token = 'tjQ5zr5EpTDqDoNFtcwTbXTmHycTTbXwodDtuh619RA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}