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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e256e48b3f4d4eea28bf35fa19b2b10b5577a0d361272e4989dedc95786de3a' 
  AND token = 'X/wBt21KnoRZEe7U3ZnFt5LXiiU3x09hiH1rCoUTD70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}