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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2deda21a8f3972d62c1022d98f450d070cf333f4cf1172e54090022440e2d2e1' 
  AND token = 'Zz7vZoqXRLaa2FONnCsLqQd/obP3HWG4kUe3GmueuAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}