SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29cefceacb4dc21df051f7290a0a60a45316a9a4c3f955f1c398a72f367ba901' 
  AND token = 'kb9FBmu2cOSnYPljkPy+8OhGRPt7gtG4urL4obqjhJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}