SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f64bcfffa0c3e749ca86f2ab87c97c228b7e959c92611aa53cdb1f6a3e5f1e' 
  AND token = 'PUv2Q77NB1uiVOHiKchbGuyEgMmx1f8Q+AIymvFI9s0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}