SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e7618c44fca56e0de9305a6d31dd6ca341d4550d3f2cd31cca9cebe9d63612' 
  AND token = '2AKacvie0TuwWYhUf3vwmg1QKFCg23l2oq/4ZOhVh0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}