SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '205360ee4a3d6b0ff565e6b52d7d4b24d0b80daee3f2e1c1869b34314e3badfa' 
  AND token = 'OKO8Q4iArO1zhjoPTuqqBEwRj5kCrJmKwqOQ+6v4Kg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}