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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c730f4ea6a67b39ab58adca95edc72af5b4d819ac9fb4a07608c548f8c7c176c' 
  AND token = 'Axm1qBokFvJmW/M0XWErfBdJ+0ymu5gNv0NpXdiupW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}