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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6df0c036c6f3e2c517d7880adc5ff2cb6b9a61cca94dde3a6ba49121fef2589' 
  AND token = '0iPTJv5k9tpamQ3Ve5YEukRSdFUETDNgjPWo82Ueeh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}