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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c890966606998772a16c0c9d5e07f39793df4c7f2a1891971493bd9b2489a280' 
  AND token = 'eR/a6DgcwIvD4HVcs5bcmdfleVBOHVD0fkdBJxX/Gpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}