SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755f136c5b1d13c5959625bfe78ce155cd25bc1e71204143ee813b3a50c7d0a1' 
  AND token = '3TKpwvfwI/hhYIRRL4XEGzSct7NW9HFAT1gBKLzya5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}