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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b8c90d6673cfb77fa0e1dc069ab017eb8dc510c7a605d5d2578389ac88410b' 
  AND token = 'lMCg31HeYCRJZ0kb9Gs5IX5ka48SXKpjzb8mAmmt/9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}