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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d2012992506c18e7920165d937b1843f1938422b7180be72ac468a5e76883dd' 
  AND token = '5R/PGZNpkOVOWo4uve95j+l805d83dsozevO9X24Ctc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}