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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ca817e9bd6e48304c8d7de378f5b1385024ece544fc3808b7599945f05641bf' 
  AND token = 'JDSUbA7sDOLtDtffo2DDe+N7R4+wAIVeKzEe9nmIJqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}