SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6487453b324f869f3e302c41fc996a0fee1e0d64913b4e1a7ebad6a74174a11' 
  AND token = 'xeVmiRl4ke+2YBBPB4Tm7Yu1HdkT+aOHUbLUPonq3vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}