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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52d3c2b8af25cbefd92d5f23c72aecf76883a9111726079f9e86239610a99365' 
  AND token = 'cLALr+Z5Nit2Ad8Oxl6j4GUG+03+lMLIEep9xfK5VAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}