SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b3a6ecccc5020acf129e85f62e460f08b25b42018a457e5834e6225f52c3337' 
  AND token = 'L+td8INXiNP4mwfF4P8Eu6qYznBQfi+mpPYxxIluxHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}