SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b5ef4070521443711a39edad90ae98ffb418ef1cb621a47f2d8ea355cbfd11e' 
  AND token = '3FSotq/SSx+UopaQBV89+GKpHaLhQ60Y23RcOyvVI5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}