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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fe1a0af89f3a8f4b4f3a824412e2388adf8fe208d22a3fbb2a4276b9314b1ad' 
  AND token = 'zHyW2Sgvzvle1RRI+KdzF4NtVHkzkdHHoKStZJoy7Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}