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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e783186595fc90141af666493f0b69324795251eb6313743561d1db54c26c0' 
  AND token = 'BiX1Qdqmz2DRHyLz7L4udO4vcuxn8vaojOpHJw8u2qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}