SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dcdd7e0c67565f7240d6c26b1179e38e57b0421c2fcd380ab98a0af36cf8428' 
  AND token = 'ESiqZZW7eL59KjVDJvawPOOIm9ndrkW2X7e4Pr5ZXKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}