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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecb5db33857f57ea6f14ff7bbc6294ef38f2ddd080dc2f35961192d8945d38a2' 
  AND token = 'ld5lpEisFzD0JONiS/BQFE5S+vs5760ZEiMgJeM3Z9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}