SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1541519d01c0cad2736868a55f084b83cf069825460c38f37ace566cbf86b3e8' 
  AND token = 'V2vkN+TmvMod3CE0j5pyKferAEU4m0HR+RhfIXCQCuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}