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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f234cfce8eecae4e5b268bff6f3bcf5d501fd543d2223e8b5895ee083160a22' 
  AND token = 'cJerCOoDf3bHC1/Fr1+UqYb1XpBejcv336KydDUlgdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}