SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df4f5b9e98034218ba3111f292666ffeb7de6400560ef436bd6520c316233797' 
  AND token = '2FpPFOF3KDHPwJZ5t2mu8OIdOuIW7Y5R2PwjNlxZg/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}