SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd425c9f8ba815f7e0238779f1a21a071c97308d459f41c263f5c29c109aa4808' 
  AND token = 'rVUfeOva4tUXsDj1BOE61rT5aFsklWvcUR6qXOM0kb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}