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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a82f12793c0b007a57587b5b953b188ff3d53d29b9c0e07415d1148f48cfc5f' 
  AND token = 'YmaCmhU7CCbwQWFAB4UCIcRYAO3+sMO5PDbdQtJKJxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}