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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a00fa49514c93cb24ffc047b2dc73b899214416447141e8ba09627857e5222bf' 
  AND token = 'S/yusR4MQYo/U4/B0PB8LULDDy2/4Ru/1JUkgGiKDDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}