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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e6667f0fb04634c3d3c79ce1b2e25538e7dd5715e70be6bda260c737521d040' 
  AND token = 'ZbkMXVdJ8ccikoa1rxR+OEcC5Ub0NAMPnGv5zrNAFnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}