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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41dceba9dc37df6fc0b87442e7de3f8e84c5919ed8ec263423d5b904ff70dd38' 
  AND token = 'cH669l6WgMnrW2ZQtZ+NrDyTW8qADtRncW9TtkN08nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}