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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '910e4a692f123e856e421fbc79daba668f7787fcb643d5ba3c648e6c3ec3b29c' 
  AND token = 'ySmvsI1brUbHL0SCTodEoALQXLrA4S8NPEJ0fOsUJWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}