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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb007b8e520981da2a2bb9f064a351c2651467f78679adcf09ba18d43fb2d0b5' 
  AND token = 'DeKa4nd1nftpOvN/vf3yWbU1DkGnRtodarKyY0yHYF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}