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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4e9da7078f7ecf55f1b6deaf49149fcc190d7c4ada5a6d55d424f60712d27f9' 
  AND token = 'HMu5j+dI2vmumeu6heb5Oe1VyrjSvxVFzzNCyFk5Gn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}