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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b6a5b2f6dfe46ec46dbec6c5df21c55d4401d8f282961b08e9101139b244cc5' 
  AND token = 'S0/ArKCm0UVs9bYWmXZDzRlA5sFOLF2Eat/IjfKgOy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}