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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b375894ef2cda1eb156078a4f79385f5ba0461c831a0ebfd4649da31e1823e0' 
  AND token = '6HYQaLI+lKPSTp8ci0qULOyL0ggMb9H/ocpOKCRgJfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}