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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a0aca3ada91a965fafcd00a49c8f25da67b6b2c85c1f3fb3c6be81a0a2be1cb' 
  AND token = '1B9xn3FDGs/DhUYmy2b37dhIB/KNeomXecQJI1oXyZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}