SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bd4c1f9845c7a80118bc569f942c0da325168a4ac7e668b0fa100d18653bcda' 
  AND token = 'bHsurayg7CsCUdC5ascJnhQoMEdSGnJvOxpPBwJ0AT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}