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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e65508712313956e702f205c840c7720768ffc763feffd25e23c479d158df51' 
  AND token = 'Rjrd0D9PKUUGS6YkIhbuOnrybty1wUE0AzHjNqTJGXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}