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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '334b3dbbb993d7fc3c1876b40ac71409afb6e07b36950f22bdf21ca4bffd7b77' 
  AND token = 'zDX1HfhaVlk+CPN5tl/4xAEV+z7lq6HSTkLhikIlx6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}