SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cd48610cc0dee1a35ea2b93c536d36e4f216abc02789670fa4ce96f17aae9f1' 
  AND token = 'Cbq8mBRmt5cgR6Hc9hkWMKDLZY5SgDj85bV7Rtpp09o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}