SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2ed8753e9de6629bf95a0ff545090c83840a581fbc40ff9842f48fa226cf8bb' 
  AND token = 'fkePWLgh+M5qW0LC33rEKvyne7Idp0V/oB/K6AAS9FA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}