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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '687f6583ea63870a0aa0cf86bab2db038bb75ddd0238b9904469d77ea868d560' 
  AND token = 'OHf4X1mk+e1chJpzHKB8QD28qoxJso4n8JqzC66/hcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}