SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5db32f6b158dc4e4fe70744ede9dc18107535c0c25f1311590106cbbaab1613f' 
  AND token = 'bXXyh9C3mgWWi9tnzkhZV2kfSnMZHu+Rg2ES6bY4zxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}