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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8f5d9204f6155939ec281b97720594b6823c12b05bf1575adfb836eaafe1a1' 
  AND token = '6YD1IB4dsTyb4WkwOoYjNnqojNbFTRD4n+Y64Eu0PTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}