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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fdc63ddbd27783bb26b2b347fc66bc227dede47958929f6d11b7a408539289b' 
  AND token = 'MSPn3PgXQW4kE3r4UTVxA4+hVt5FzF2zAJ0p4szQiSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}