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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec55e787fb4e64dd00d94f6ba00d84923e6770ba7c21b2651a3c083462ca9612' 
  AND token = 'Mvs4YPWxEzWCPVYWtBD1bkRognZIbJdCYv8nZMgsoOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}