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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd647240b4b4ce2f2769478fcc260b84ba3a48b7235052d3181ff078b551b450a' 
  AND token = 'd9YqeOxeXsiqjjRbhwyb+F8fFcV7ptB4z/przAHntnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}